Current Funding in the Fox Lab

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The Fox Lab has recieved grants for a number of ongoing projects, in addition to support from UC Davis and the California National Primate Research Center.

Here are some of the most recent grants to give you an idea of what we are working on.

  • Origins and Emergence of Maladaptive Socioemotional Behavior During the Transition to Adulthood in Primates

    This proposal uses multi-modal neuroimaging and machine-learning-based behavioral analysis to study behavioral inhibition in nonhuman primates. NIH: R01 MH121735 (PI: Fox)

  • Rethinking the Neural Correlates of Uncertain Threat Anticipation with a Statistical Learning Approach

    This study uses a novel computational model and functional MRI to understand the neural correlates of temporally uncertain threat anticipation. NIH: R21 MH129851 (PI: Fox)

  • Using Theory- and Data-Driven Neurocomputational Approaches and Digital Phenotyping to Understand RDoC Acute and Potential Threat

    This study uses a computational approach in combination with functional MRI and cell-phone based experience sampling to understand the neural correlates of uncertain threat anticipation. NIH: R01 MH131264 (PI: Shackman)

  • Engineered AAV Identification, Validation, and Dissemination Pipeline for Brain Cell Type-Specific Manipulation Across Species

    Through this proposal, the Fox lab aims to develop and validate novel viral vectors that can be used in nonhuman primates to deliver cutting-edge reporters, effectors, and sensors. This tool development is necessary to determine the specific cells/projections that give rise to the experience of anxiety. NIH: U01 MH128336 (Co-PIs: Gradinaru, Tian, Fox)

  • Gut-to-brain circuit contributions to Parkinson-like phenotypes in non-transgenic rodent and primate animal models

    This proposal the Fox lab aims to leverage recently developed neuroscientific tools to understand Parkinson’s relevant brain circuits. This proposal involves the development of new tools for high-throughput analysis of primate brain circuits. Aligning Science Across Parkinson’s: ASAP-020495 (Team Leader: Gradinaru, Co-PI: Fox)

  • Wireless Optogenetic Stimulation to Illuminate the Effects of Cortex on Behavioral Inhibition

    This is a pilot study to provide a proof of principle for wireless projection-specific optogenetic manipulation in non-human primates. This will be the first study to manipulate cortical projections to subcortical structures involved in the generation of anxiety. UC Davis Behavioral Health Center of Excellence (PI: Fox)

If you want to know more, you can email Drew.